SD-OCT can directly measure and quantify RNFL thickness by calculating the area between the internal limiting membrane (ILM) and RNFL border (how the edge of the RNFL is determined and how blood vessels are handled are different among the machines, which do not have interchangeable measurement outputs). Glaucoma is a group of many conditions sharing a final common pathway characterized by accelerated death of retinal ganglion cells and their retinal nerve fiber layer (RNFL) axons resulting in characteristic visual field defects and corresponding optic nerve head anatomical changes. Our review focuses on the Cirrus HD-OCT in diagnosing glaucoma and glaucoma progression. Each machine has different glaucoma scan patterns, proprietary software segmentation algorithms, and display outputs. Ultrahigh speed swept source OCT, ultrahigh resolution OCT, polarization sensitive OCT, and adaptive optics OCT are all on the horizon.Ĭurrently, the most common four commercially available SD-OCT devices in the US are: Cirrus HD-OCT (Carl Zeiss Meditec, Dublin, CA, USA), RTVue-100 (Optovue Inc., Fremont, CA, USA), Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany), and Topcon 3D-OCT 2000 (Topcon Corporation, Tokyo, Japan). Only four years later, several companies started to release the next generation technology, spectral-domain OCT (SD-OCT), AKA fourier-domain OCT, which improved upon TD-OCT by capturing more data in less time at a higher axial image resolution, around 5 µm. OCT became widely popular in 2002 with the release of Stratus OCT, a time-domain technology (TD-OCT) that was well-studied and validated for use in glaucoma and retina and went on to become a standard structural imaging test. Automated software segmentation algorithms are able to outline the retinal nerve fiber layer with much precision, which is relevant in glaucoma since this layer is thinned as ganglion cells are lost. Optical coherence tomography (OCT), first described in 1991, is a noncontact, noninvasive imaging technique that can reveal layers of the retina by looking at the interference patterns of reflected laser light. It will provide a brief review of all modalities, but focus primarily on the Cirrus machine. This is a review of the utility of spectral-domain optical coherence tomography in the diagnosis and management of glaucoma. 5.6 Correlation of OCT with Visual Field.5.1 Repeatability and Reproducibility of SD-OCT.5 Use of SD-OCT in Detection of Glaucomatous Progression.4 Use of SD-OCT in Diagnosis of Glaucoma.*OCT Angiography is under development and not for sale yet. OCT Angiography will build on the OCT2 Module. Right: OCT Angiography of an old BRVO with visible changes in the deep vascular network, clearly seen between inferior and superior. Left: OCT Angiography of the deep vascular network in a healthy eye. In our opinion, this represents a significant value to customers and the concept of expandability is a major reason why eye care professionals all around the world consider our products an excellent choice, not only from a clinical but also from an economical perspective.” Jörg Pintaske, Head of Marketing at Heidelberg Engineering adds, “In today’s rapid pace of technological evolution, the company’s commitment to sustainability and value proposition is something that is not often seen in the medical device business. I’m confident that our customers will be delighted with this even more powerful engine.”ĭr. This is an important achievement and further substantiates the sound technology pathway we have defined. Kester Nahen, Managing Director at Heidelberg Engineering states, “Over the last months, our team in Heidelberg was able to increase the scan rate of the OCT2 Module from 70,000 Hz to 85,000 Hz. Introduced with an already high scan rate of 70,000 Hz, Heidelberg Engineering was able to achieve another significant improvement in the acquisition speed.ĭr. In addition, a large number of SPECTRALIS devices in use, depending on their technical specifications, can be upgraded with the OCT2 Module. Since its debut at the 2014 American Academy of Ophthalmology in Chicago, the OCT2 Module is an option for all new SPECTRALIS models. New applications such as OCT Angiography* will build on the OCT2 Module. It combines a high scan rate with Heidelberg Engineering’s proprietary TruTrack Active Eye Tracking, to provide unmatched image quality and significantly improved acquisition speed. The OCT2 Module brings the next generation OCT technology to the SPECTRALIS diagnostic imaging platform. Heidelberg, Germany - Heidelberg Engineering announces significant improvements to the SPECTRALIS ® OCT2 Module. New Module Exhibited at American Society of Cataract and Refractive Surgery, Booth #2139
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